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Robert Winston's SUPERHUMAN ABC TV Thursday 1.00 PM
Injecting
a virus directly into the cancer tuma stunted growth.
Robert
Swan was the first • drilled a hole and injected direct into
the
brain/tuma herpes simplex - the same virus that causes cold sores -
it's particularly effective at destroying rapidly dividing cells.
Prof.
Moira Brown
Glasgow
Southern General Hospital
"In
the brain most of the cells are no longer diving - so could this be
used as a therapeutic tool?"
4
years later - It hasn't shrunk but it has stopped growing - he has
checkups with Dr Ramplings - scans show tuma is static and no sign the
virus has escaped to do any harm.
http://www.gla.ac.uk/clinicalneuroscience/staffbrown.html
Professor Moira Brown is a virologist at Glasgow
University, where she
has developed a strain of herpes virus (strain 1716) which only
replicates (grows) in rapidly dividing cells, including cancerous
cells. This genetically modified virus can be injected into brain
tumours, where it grows, killing the cancer cells. But when the virus
reaches the edge of the tumour and healthy brain tissue, which does not
contain rapidly dividing cells, the virus stops growing. Moira's team
are now also investigating the potential of this type of therapy in
other types of tumours elsewhere on the body, including malignant
melanoma.
A herpes simplex virus, as
seen
under the electron microscope. The
outer (white) layer is the viral envelope. The nucleo-capsid (the
central white 'core') contains the viral DNA. http://www.thenakedscientists.com/index.htm?HTML/Guestfile/moirabrown.htm~mainFrame
CRUSADE LABORATORIES
HSV1716 in head and neck cancer
The most common type of malignant tumour in the head
and neck region is squamous cell carcinoma. Squamous cells make up the
linings of the mouth, nose and throat.
A Phase II trial in 20 patients with squamous cell
carcinoma of the head and neck started in March 2002. Recruitment of
patients for this trial is in progress.
The clinical trials
are carried out at the Institute of Neurological Sciences (INS) at the
Southern General Hospital.
CLICK HERE to SEARCH for "Moira Brown HSV1716" IN GOOGLE
http://www.google.com/search?q=Moira+Brown+HSV1716&ie=UTF-8&oe=UTF-8
GERM
WARFARE
Not
all bacteria are bad, and some diseases can even help to defeat
others. Killers into Cures meets Robert Swan, who volunteered to have
the herpes virus injected into his brain in a bold bid to halt the
growth of an inoperable tumour. Four years on, the results have been
remarkable. ...more
"Engineering Reproduction: Will We Still Be Human At The End of the
21st Century"
by Professor Lord Robert Winston
Capitol Theatre
Sunday, May 13, 2001, 6pm
http://www.abc.net.au/rn/deakin/stories/s291481.htm
HIV/AIDS
infection…
HIV (Human Immunodeficiency virus) is cause of Aids and
was discovered
20 years ago. There are over 42 million sufferers of HIV worldwide and
infects the CD4 T cells (chiefs of the immune system) where they kill
and stop them from working properly. These cells replace themselves and
eventually the virus overwhelms the immune system. Treatment had
started for Aids in 1981, HIV in 1983 and the A2T drug was developed in
1987 to treat the HIV virus. From 1996 the triple therapy was the
standard therapy. However these 3 classes of drugs is not considered a
cure - simply for the reasons that the drugs have to be taken forever,
and not all sufferers have equal access to it and the treatment can be
ineffective if missed on occasions. A major issue concerning the HIV
virus is that it is hardly recognizable. The HIV virus is coated with
sugar molecules and triggers to produce the wrong antibodies; this
integrates into the human DNA and cannot be recognized very well.
http://www.lboro.ac.uk/admin/committees/prizes/02-03/leb/03leb.htm
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